Exploring the theranostic potential of two metabolically stable GRPR-targeting peptides labelled with Ga-68 for PET imaging
[<sup>68</sup>Ga]Ga-PKB2 and [<sup>68</sup>Ga]Ga-PKB3 are promising PET tracers for imaging of GRPR-positive tumours and are potential diagnostic counterparts to their <sup>177</sup>Lu-labelled analogues, supporting their use as a <sup>177</sup>Lu/<sup>68</sup>Ga theranostic pair.
Authors
- Panagiotis Kanellopoulos (ORCID: https://orcid.org/0000-0002-0617-3936)
- Vladimir Tolmachev (ORCID: https://orcid.org/0000-0002-6122-1734)
- Karim Obeid
- Ekaterina A. Bezverkhniaia
- Anna Orlova
Institutions
- Uppsala University (SE)
- Science for Life Laboratory (SE)
Publication Details
- Journal
- EJNMMI Radiopharmacy and Chemistry
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1186/s41181-026-00431-5
- Primary Topic
- Neuropeptides and Animal Physiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00