Ginsenoside Rg3 Ameliorates Psoriasis‐Like Dermatitis through Inhibition of NF‐κB/NLRP3 Inflammasome Signaling and Regulating Th17/Treg Balance
Our findings indicate that Grg3 confers protective effects in a murine model of imiquimod-induced psoriasis-like dermatitis. The potential therapeutic properties of Grg3 potentially involve modulation of NLRP3 inflammasome activation, suppression of NF-κB signaling, and restoration of Th17/Treg cell homeostasis.
Authors
- Zhen Yue
- Zhaoli Zhou (ORCID: https://orcid.org/0000-0003-4217-2567)
- Wanlu Zhang (ORCID: https://orcid.org/0000-0002-7119-1874)
- Huiya Sun
- Qingge Xie
- Liyun Gao
- Congjun Jiang
Institutions
- Bengbu Medical College (CN)
- Anhui University of Finance and Economics (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/iid3.70362
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00