Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation
This study highlights the intricate balance of cellular proliferation, programmed cell death, matrix remodeling, and vacuolation dynamics as key determinants in shaping the NP along the rostro-caudal axis.
Authors
- Anne Camus (ORCID: https://orcid.org/0000-0002-8820-0407)
- Pauline Colombier
- Lily Paillat
- Julie Warin (ORCID: https://orcid.org/0009-0008-0069-9428)
- Estelle Balissat
Institutions
- Inserm (FR)
- Nantes Université (FR)
Publication Details
- Journal
- Developmental Dynamics
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1002/dvdy.70119
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Biogen
- Infrastructures en Biologie Santé et Agronomie
- Agence Nationale de la Recherche
- Institut National de la Santé et de la Recherche Médicale
- Centre National de la Recherche Scientifique