The infection-inducible chitin deacetylase AwCDA1 drives virulence in postharvest fungus Aspergillus westerdijkiae
AwCDA1 is a postharvest infection-inducible virulence factor in A. westerdijkiae that weakens host immune recognition and regulates OTA biosynthesis. Its responsiveness to chitin-related signals and Zn<sup>2+</sup>-dependent activity supports postharvest fruit colonization. BHA inhibition validates AwCDA1 as a promising antifungal target, offering insights for sustainable OTA control.
Authors
- Yanhua Fan (ORCID: https://orcid.org/0000-0001-6261-0961)
- Fuguo Xing
- Yibing Liu (ORCID: https://orcid.org/0000-0003-4420-215X)
- Xi Zhang (ORCID: https://orcid.org/0000-0002-4638-3997)
- Fei Pan
- Gang Wang
Institutions
- Southwest University (CN)
- Institute of Food Science and Technology (CN)
- Ministry of Agriculture (HU)
- Institute of Agro-Products Processing Science and Technology (CN)
- Chinese Academy of Agricultural Sciences (CN)
- Institute of Apiculture Research (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.jare.2026.02.024
- Primary Topic
- Fungal and yeast genetics research
- Type
- article
- Field-Weighted Citation Impact
- 0.00