VMAT-based total body irradiation on a conventional LINAC: workflow, procedure and preliminary results

Our study demonstrates that VMAT-based TBI is a feasible and promising alternative to conventional 2D-TBI, providing improved dose homogeneity, enhanced organ sparing and with reproducibility comparable to previously reported HT systems. These findings support the integration of VMAT techniques on conventional LINACs for TBI treatments, although further prospective studies are needed to confirm long-term clinical benefits.