The JAK1-STAT1 signaling pathway triggers inflammation responses in chronic obstructive sleep apnea rat model

JAK1-STAT1 signaling critically mediates CIH-induced inflammation. JAK1 inhibition attenuates inflammatory responses, demonstrating therapeutic potential for OSA comorbidities.

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Publication Details

Journal
PLoS ONE
Published
2026-02-17
DOI
https://doi.org/10.1371/journal.pone.0343053
Primary Topic
Obstructive Sleep Apnea Research
Type
article
Field-Weighted Citation Impact
0.00
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article

The JAK1-STAT1 signaling pathway triggers inflammation responses in chronic obstructive sleep apnea rat model

Lin F. Yang, Jie He
PLoS ONE
Obstructive Sleep Apnea Research
article

The JAK1-STAT1 signaling pathway triggers inflammation responses in chronic obstructive sleep apnea rat model

Lin F. Yang, Jie He
article en

Abstract

JAK1-STAT1 signaling critically mediates CIH-induced inflammation. JAK1 inhibition attenuates inflammatory responses, demonstrating therapeutic potential for OSA comorbidities.

PLoS ONEVol. 21(2)
First Affiliated Hospital of Chengdu Medical College (CN), The Fourth People's Hospital of Ningxia Hui Autonomous Region (CN)
Good health and well-being
Openalex Percentile: Top 51%
Obstructive Sleep Apnea Research
DOIOpen Access PDFOpenAlex
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The JAK1-STAT1 signaling pathway triggers inflammation responses in chronic obstructive sleep apnea rat model — Lin F. Yang, Jie He · PLoS ONE (2026) | TGRS Research Map | TGRS