Intralesional bevacizumab as an adjuvant approach to recurrent respiratory papillomatosis: A prospective study on different treatment protocols

This study indicates that both dosing regimens of bevacizumab were effective as an adjunctive therapy of recurrent respiratory papillomatosis. The higher intralesional doses of bevacizumab are relatively safe and well tolerated in adult patients with laryngeal RRP. Further studies with extended follow-up are warranted to define long-term efficacy and optimal dosing strategies.

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Publication Details

Journal
PLoS ONE
Published
2026-02-17
DOI
https://doi.org/10.1371/journal.pone.0342749
Primary Topic
Voice and Speech Disorders
Type
article
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article

Intralesional bevacizumab as an adjuvant approach to recurrent respiratory papillomatosis: A prospective study on different treatment protocols

Andrzej Porębski, Hanna Klimza, Małgorzata Wierzbicka, Bartosz Zakrzewski
PLoS ONE
Voice and Speech Disorders
article

Intralesional bevacizumab as an adjuvant approach to recurrent respiratory papillomatosis: A prospective study on different treatment protocols

Andrzej Porębski, Hanna Klimza, Małgorzata Wierzbicka, Bartosz Zakrzewski
article en

Abstract

This study indicates that both dosing regimens of bevacizumab were effective as an adjunctive therapy of recurrent respiratory papillomatosis. The higher intralesional doses of bevacizumab are relatively safe and well tolerated in adult patients with laryngeal RRP. Further studies with extended follow-up are warranted to define long-term efficacy and optimal dosing strategies.

PLoS ONEVol. 21(2)
Wrocław University of Science and Technology (PL), Jagiellonian University (PL), Institute of Human Genetics (PL), Wroclaw Research Centre EIT+ (Poland) (PL), AGH University of Krakow (PL), Polish Academy of Sciences (PL)
Good health and well-being
Openalex Percentile: Top 51%
Voice and Speech Disorders
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Intralesional bevacizumab as an adjuvant approach to recurrent respiratory papillomatosis: A prospective study on different treatment protocols — Andrzej Porębski, Hanna Klimza, et al. · PLoS ONE (2026) | TGRS Research Map | TGRS