Vital-affective symptom connectivity during electroconvulsive therapy distinguishes depression remission outcomes: A cross-lagged panel network study
Reductions in suicidal thoughts preceded broader symptom improvements, suggesting this symptom warrants monitoring. Remitters showed coordinated symptom reduction where affective and vital symptoms reinforced each other, while non-remitters showed independent reduction. These findings provide insights into symptom dynamics during ECT.
Authors
- Edwin van Dellen (ORCID: https://orcid.org/0000-0003-1828-5959)
- Mardien L. Oudega (ORCID: https://orcid.org/0000-0002-1521-1682)
- Esmée Verwijk
- Melissa Zandstra
- Gabriela Lunansky (ORCID: https://orcid.org/0000-0001-6226-2258)
- J.M. Hegeman
- Dieneke Bloemkolk
- Dore Loef (ORCID: https://orcid.org/0000-0002-4443-0139)
- Alex O. Rothbaum (ORCID: https://orcid.org/0000-0003-0593-1552)
- Frank L. Gerritse (ORCID: https://orcid.org/0000-0002-5825-050X)
- Didi Rhebergen (ORCID: https://orcid.org/0000-0002-3741-9767)
- Indira Tendolkar (ORCID: https://orcid.org/0000-0003-3171-3671)
- Willemijn T. Heijnen (ORCID: https://orcid.org/0000-0002-7390-1606)
- R.M. Kok
- Jasper O. Nuninga (ORCID: https://orcid.org/0000-0001-8901-8140)
- H. van Welie
- Noor Woerdman
- Bart Schut
- E. van Exel
- B. Broekman
- A. Dols
- Tom K. Birkenhager
- Roel J.T. Mocking
- Floortje E. Scheepers
- Rosanne Turner
- Henricus G. Ruhe
- Philip van Eijndhoven
- Iris E. Sommer
- Metten Somers
Institutions
- Radboud University Nijmegen (NL)
- University of Antwerp (BE)
- Utrecht University (NL)
- Maastricht University Medical Centre (NL)
- Radboud University Medical Center (NL)
- University Medical Center Utrecht (NL)
- Parnassia Groep (NL)
- GGz centraal (NL)
- St. Antonius Ziekenhuis (NL)
- Amsterdam Neuroscience (NL)
- Dialyse Centrum Groningen (NL)
- GGZ inGeest (NL)
- Tergooi (NL)
- Amsterdam University Medical Centers (NL)
- Pro Persona (NL)
- Amsterdam University of Applied Sciences (NL)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Brain stimulation
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1016/j.brs.2026.103058
- Primary Topic
- Mental Health Research Topics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- ZonMw