A structured proactive penicillin allergy delabeling intervention in adult patients in three non-university hospitals

A screening tool for proactive detection of penicillin allergy was developed. This study demonstrates that a substantial proportion of patients with a presumed penicillin allergy can be delabeled non-medically by administering a structured questionnaire, offering a step up towards comprehensive allergologic questioning and patient file analysis, with eventual additional testing in selected patients. The screening tool needs to be validated in a prospective trial including definitive categorization.