Neutrophil Gelatinase–Associated Lipocalin Drives Cardiac Remodeling in Rats With Chronic Kidney Disease
In CKD rats, Ngal was involved in cardiac remodeling via a Gal-3/Tlr4-dependent pathway, increasing inflammation and fibrosis, and correlated to cardiac outcomes in the MEDIA-DHF and BIOSTAT-CHF cohorts.
Authors
- Zohra Lamiral (ORCID: https://orcid.org/0000-0001-7349-7124)
- Tania Sánchez‐Bayuela (ORCID: https://orcid.org/0000-0003-4773-7037)
- Matthieu Soulié (ORCID: https://orcid.org/0000-0002-5169-1628)
- Yohan Stephan (ORCID: https://orcid.org/0000-0002-2470-0058)
- Paul Mulder
- J Frederic
- Jeremy Lagrange
- N Lopez-Andres
- Ixchel Lima-Posada
- Adriaan Voors
- Nicolas Girerd
- Lionel Nicol
Institutions
- University Medical Center Groningen (NL)
- Inserm (FR)
- Sorbonne Université (FR)
- Normandie Université (FR)
- Navarrabiomed (ES)
- Fondation pour l’innovation en Cadiométabolisme et Nutrition (FR)
- French Clinical Research Infrastructure Network (FR)
- Université de Rouen Normandie (FR)
Publication Details
- Journal
- Hypertension
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1161/hypertensionaha.125.25658
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00