The Impact of Surgical Resection in Early Onset Colorectal Cancer Patients With Liver Limited Disease

The results indicate a worse overall prognosis for EO-CRC patients undergoing metastasectomy compared to average-onset patients. This outcome appears to occur independently of the molecular status. These observations could have a considerable impact on clinical practice and research.

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Publication Details

Journal
Clinical Colorectal Cancer
Published
2026-02-01
DOI
https://doi.org/10.1016/j.clcc.2026.02.002
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
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article

The Impact of Surgical Resection in Early Onset Colorectal Cancer Patients With Liver Limited Disease

Andrea Pretta, Gianluca Pretta, Alberto Giovanni Leone, Riccardo Cerantola et al.
Clinical Colorectal Cancer
Hepatocellular Carcinoma Treatment and Prognosis
article

The Impact of Surgical Resection in Early Onset Colorectal Cancer Patients With Liver Limited Disease

Andrea Pretta, Gianluca Pretta, Alberto Giovanni Leone, Riccardo Cerantola, Valeria Pusceddu, Filippo Ghelardi, MARIO SCARTOZZI, Stefano Mariani, Pina Ziranu, Gianmarco Ricagno, Clelia Donisi, SARA LONARDI, Erika Cimbro, F. Pietrantonio, Ada Taravella, Eleonora Perissinotto, K. Cerma, Chiara Cremolini, Mariapaola Masiello, Alessia Lancianese, Andrea Bottelli, Federica Marmorino, Raffaele Squitieri, Riccardo Giampieri, Paolo Ciracì, Luca Papini
article en

Abstract

The results indicate a worse overall prognosis for EO-CRC patients undergoing metastasectomy compared to average-onset patients. This outcome appears to occur independently of the molecular status. These observations could have a considerable impact on clinical practice and research.

Clinical Colorectal Cancer
Marche Polytechnic University (IT), University of Cagliari (IT), Istituto Oncologico Veneto (IT), King's College School (GB), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Fondazione IRCCS Istituto Nazionale dei Tumori (IT), Azienda Ospedaliera Universitaria Pisana (IT)
Good health and well-being
Openalex Percentile: Top 53%
Hepatocellular Carcinoma Treatment and Prognosis
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