Unraveling the role of LINC02657 in clear cell renal cell carcinoma: insights into tumor aggression, immune modulation, and treatment response
LINC02657 is a critical oncogenic lncRNA in ccRCC, promoting tumor progression by regulating cell cycle, EMT, and immune microenvironment. It serves as a robust independent prognostic biomarker and a potential therapeutic target, offering valuable insights for personalized ccRCC treatment strategies.
Authors
- Hongbing Mei (ORCID: https://orcid.org/0000-0002-6009-4753)
- Hao Wang (ORCID: https://orcid.org/0000-0001-6881-9977)
- Yang Liu (ORCID: https://orcid.org/0000-0001-9391-5493)
- Aifa Tang
- Juncheng Tong
- L. Liu
- Cheng Qian
- Xiangguo Xiong
- Zhenqing Fan
Institutions
- Shantou University (CN)
- Shantou University Medical College (CN)
- Shenzhen Luohu People's Hospital (CN)
- Jingning County People's Hospital (CN)
- Shenzhen Second People's Hospital (CN)
- Yuxian People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-17
- DOI
- https://doi.org/10.3389/fimmu.2026.1735169
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00