Automated Near Real‐Time QC for LC‐HRMS

These capabilities enable immediate detection, triage and documentation of performance excursions, support proactive maintenance (e.g., column aging or pump delivery issues), minimise downtime and safeguard precious samples. Although showcased on a specific LC-HRMS setup and matrix, the workflow is instrument-agnostic and broadly applicable to internal-standardised LC-HRMS methods.

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Publication Details

Journal
Rapid Communications in Mass Spectrometry
Published
2026-02-17
DOI
https://doi.org/10.1002/rcm.70052
Primary Topic
Isotope Analysis in Ecology
Type
article
Field-Weighted Citation Impact
0.00
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article

Automated Near Real‐Time QC for LC‐HRMS

Jan H. Christensen, Michael Möhr, Rudi Winzenbacher, Wolfram Seitz et al.
Rapid Communications in Mass Spectrometry
Isotope Analysis in Ecology
article

Automated Near Real‐Time QC for LC‐HRMS

Jan H. Christensen, Michael Möhr, Rudi Winzenbacher, Wolfram Seitz, Tobias Bader, Linus Strähle, Pia Leurle
article en

Abstract

These capabilities enable immediate detection, triage and documentation of performance excursions, support proactive maintenance (e.g., column aging or pump delivery issues), minimise downtime and safeguard precious samples. Although showcased on a specific LC-HRMS setup and matrix, the workflow is instrument-agnostic and broadly applicable to internal-standardised LC-HRMS methods.

Rapid Communications in Mass SpectrometryVol. 40(10)
University of Copenhagen (DK), Landeswasserversorgung (Germany) (DE)
Clean water and sanitation
Openalex Percentile: Top 59%
Isotope Analysis in Ecology
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