A population-based, regression discontinuity analysis examined the effects of nationwide alerting for acute kidney injury on health care and patient outcomes
We found no causal evidence that AKI e-alerts (specifically implemented at a 50% creatinine rise threshold) improved or worsened clinical outcomes in this nationwide real-world evaluation. Consistently poor outcomes, limited documentation and follow-up care, even in the presence of e-alerts, underscore the need for an improved clinical response to AKI.
Authors
- Sawhney Simon
- Tim Scale
- Pascal Geldsetzer (ORCID: https://orcid.org/0000-0002-8878-5505)
- Matthew James
- Tom Blakeman
- Min Xie
- Zhi Tan
Institutions
- Swansea Bay University Health Board (GB)
- University of Calgary (CA)
- University of Aberdeen (GB)
- Heidelberg University (DE)
- Manchester Academic Health Science Centre (GB)
- University Hospital Heidelberg (DE)
- University of Manchester (GB)
- O'Brien Institute (AU)
- NHS Grampian (GB)
- Stanford Health Care (US)
- Libin Cardiovascular Institute of Alberta (CA)
- Stanford University (US)
Publication Details
- Journal
- Kidney International
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.kint.2026.01.019
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00