Primary radiotherapy for intraorbital solitary fibrous tumor: a case report with 5-year follow-up

Orbital solitary fibrous tumors (OSFTs) are rare, usually benign spindle-cell neoplasms predominantly treated with complete surgical excision. In cases where the tumor is anatomically complex or surgical morbidity is high, alternative therapies may be considered. Here we report, to our knowledge, the first case of an OSFT successfully managed with primary stereotactic radiotherapy. The patient, a 69-year-old woman, showed sustained tumor regression and clinical improvement over a 5-year follow-up period without evidence of malignant transformation. This case demonstrates that primary radiotherapy may be a safe and effective alternative in select OSFT cases where surgery poses risks.

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Publication Details

Journal
Orbit
Published
2026-02-16
DOI
https://doi.org/10.1080/01676830.2026.2620121
Primary Topic
Soft tissue tumor case studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Primary radiotherapy for intraorbital solitary fibrous tumor: a case report with 5-year follow-up

Dion Paridaens, H. Abusaris, R. Stokman, R. M. Verdijk
Orbit
Soft tissue tumor case studies
article

Primary radiotherapy for intraorbital solitary fibrous tumor: a case report with 5-year follow-up

Dion Paridaens, H. Abusaris, R. Stokman, R. M. Verdijk
article en

Abstract

Orbital solitary fibrous tumors (OSFTs) are rare, usually benign spindle-cell neoplasms predominantly treated with complete surgical excision. In cases where the tumor is anatomically complex or surgical morbidity is high, alternative therapies may be considered. Here we report, to our knowledge, the first case of an OSFT successfully managed with primary stereotactic radiotherapy. The patient, a 69-year-old woman, showed sustained tumor regression and clinical improvement over a 5-year follow-up period without evidence of malignant transformation. This case demonstrates that primary radiotherapy may be a safe and effective alternative in select OSFT cases where surgery poses risks.

OrbitVol. 45(2)
University Medical Center (US), Rotterdam Eye Hospital (NL)
Good health and well-being
Openalex Percentile: Top 54%
Soft tissue tumor case studies
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