AMACR and ZFPL1 serum biomarkers enhance precision in predicting postoperative prostate cancer outcomes
Elevated serum AMACR and ZFPL1 levels independently predict recurrence following radical prostatectomy in patients with PCa. The proposed nomogram integrates molecular and clinicopathological factors to provide accurate postoperative risk stratification, supporting individualized follow-up and management, with robust performance observed up to 3 years after surgery.
Authors
- Gangli Gu (ORCID: https://orcid.org/0000-0002-6699-0153)
- Renguang Lv
- Lin Yang (ORCID: https://orcid.org/0000-0002-9318-9812)
- Zhao Liu
- Gang Chen
Institutions
- Fourth People’s Hospital of Jinan (CN)
- Seventh People's Hospital of Shanghai (CN)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-02-17
- DOI
- https://doi.org/10.3389/fonc.2026.1625125
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00