Smoking and Clostridioides difficile Colonization in Adults Aged ≥40 Years: Findings from a Community-Based Gut Microbiota Study

Cigarette smoking was associated with an increased likelihood of community-acquired CdC in southern Taiwan. Distinct gut microbiota profiles were observed in individuals with CdC, supporting a potential link between smoking-related microbiota alterations and susceptibility to asymptomatic colonization. These findings underscore the relevance of modifiable lifestyle factors in the epidemiology of community CdC and warrant further investigation.

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Publication Details

Journal
Infection and Drug Resistance
Published
2026-02-01
DOI
https://doi.org/10.2147/idr.s571988
Primary Topic
Clostridium difficile and Clostridium perfringens research
Type
article
Field-Weighted Citation Impact
0.00

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article

Smoking and Clostridioides difficile Colonization in Adults Aged ≥40 Years: Findings from a Community-Based Gut Microbiota Study

Hung YP, Hongming Chen, Tian Yang, Wen-Chien Ko et al.
Infection and Drug Resistance
Clostridium difficile and Clostridium perfringens research
article

Smoking and Clostridioides difficile Colonization in Adults Aged ≥40 Years: Findings from a Community-Based Gut Microbiota Study

Hung YP, Hongming Chen, Tian Yang, Wen-Chien Ko, Pei-Jane Tsai, Chin-Shiang Tsai
article en

Abstract

Cigarette smoking was associated with an increased likelihood of community-acquired CdC in southern Taiwan. Distinct gut microbiota profiles were observed in individuals with CdC, supporting a potential link between smoking-related microbiota alterations and susceptibility to asymptomatic colonization. These findings underscore the relevance of modifiable lifestyle factors in the epidemiology of community CdC and warrant further investigation.

Infection and Drug ResistanceVol. Volume 19
National University of Tainan (TW), Chest Hospital, Ministry of Health and Welfare (TW), National Cheng Kung University Hospital (TW), National Cheng Kung University (TW)
National Cheng Kung University Hospital, National Cheng Kung University
Good health and well-being
Openalex Percentile: Top 52%
Clostridium difficile and Clostridium perfringens research
DOIOpen Access PDFOpenAlex
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