Urinary extracellular vesicle metabolomic profiling reveals a distinct molecular signature for the non-invasive diagnosis of lupus nephritis
We identified a distinct uEV metabolic signature in LN and developed a robust, non-invasive biomarker panel. This strategy holds significant promise for the early detection and personalized management of LN, offering a compelling alternative to invasive renal biopsy.
Authors
- Ting Liu (ORCID: https://orcid.org/0000-0003-3065-8367)
- Yanjing Rui
- Adeel Khan (ORCID: https://orcid.org/0000-0001-8766-0551)
- Nan Zhang (ORCID: https://orcid.org/0009-0002-7245-0695)
- Ping Yang
- Ning Dong
- Anran Xie
Institutions
- Nanjing Drum Tower Hospital (CN)
- University of Science and Technology Bannu (PK)
- Pharmaceutical Biotechnology (Czechia) (CZ)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-17
- DOI
- https://doi.org/10.3389/fimmu.2026.1741455
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nanjing University
- Nanjing Drum Tower Hospital