Is it safe to preserve uterus after live birth following progestin‐based fertility‐sparing treatment for endometrial cancer or atypical hyperplasia: A long‐term retrospective cohort study

Although live birth was associated with improved recurrence-free survival in patients with EC or AEH receiving FST, postpartum recurrence remains a concern. Irregular menstruation and abnormal ultrasound findings were identified as key risk factors for recurrence, while maintenance therapy exhibited a protective effect. These findings highlight the need for vigilant postpartum monitoring in this population.

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Publication Details

Journal
Acta Obstetricia Et Gynecologica Scandinavica
Published
2026-02-17
DOI
https://doi.org/10.1111/aogs.70139
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Is it safe to preserve uterus after live birth following progestin‐based fertility‐sparing treatment for endometrial cancer or atypical hyperplasia: A long‐term retrospective cohort study

Yifan Feng, Qun Lu, Linlin Bo, Hao Wang et al.
Acta Obstetricia Et Gynecologica Scandinavica
Endometrial and Cervical Cancer Treatments
article

Is it safe to preserve uterus after live birth following progestin‐based fertility‐sparing treatment for endometrial cancer or atypical hyperplasia: A long‐term retrospective cohort study

Yifan Feng, Qun Lu, Linlin Bo, Hao Wang, Zerui Xiao, R. Huang F. L. Zhou, Yiqin Wang, Yuanyuan Liu, Li Tian, Jianliu Wang
article en

Abstract

Although live birth was associated with improved recurrence-free survival in patients with EC or AEH receiving FST, postpartum recurrence remains a concern. Irregular menstruation and abnormal ultrasound findings were identified as key risk factors for recurrence, while maintenance therapy exhibited a protective effect. These findings highlight the need for vigilant postpartum monitoring in this population.

Acta Obstetricia Et Gynecologica Scandinavica
Capital Medical University (CN), Peking University (CN), Beijing Chao-Yang Hospital, Capital Medical University (CN), Peking University People's Hospital (CN)
National Natural Science Foundation of China, Peking University, Peking University People's Hospital
Good health and well-being
Openalex Percentile: Top 54%
Endometrial and Cervical Cancer Treatments
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Is it safe to preserve uterus after live birth following progestin‐based fertility‐sparing treatment for endometrial cancer or atypical hyperplasia: A long‐term retrospective cohort study — Yifan Feng, Qun Lu, et al. · Acta Obstetricia Et Gynecologica Scandinavica (2026) | TGRS Research Map | TGRS