Sensor ToolKit (STK): Compact Multiplexing Potentiostat for Point-of-Care Applications

Embedded potentiostats have enabled the possibility of implementing electrochemical applications in a wide range of areas, from industry to healthcare. However, the optimization for either small size, low-cost devices, or sensor interfacing in existing platforms may lead to impractical outcomes. In this work, we propose Sensor ToolKit (STK), prototyped using off-the-shelf components and engineered to be a highly versatile, small, and low-cost platform of minimal complexity for the deployment of distributed IoT electrochemical sensors applications. The board implements an on-chip sequential input multiplexer that is especially suited for open-circuit potentiometry studies. The performance of the board was validated in potentiometric detection of potassium, hydrogen peroxide, glucose, and lactate, as well as self-current detection of hydrogen peroxide. Results show excellent analytical performance, comparable to that of benchtop instrumentation standards. The developed firmware and IoT framework enable the retrieval of sensor data wirelessly by a remote data server, which automates its real-time visualization using the Grafana web application, highlighting the potential of STK in distributed hyperconnected applications.

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Publication Details

Journal
Analytical Chemistry
Published
2026-02-17
DOI
https://doi.org/10.1021/acs.analchem.5c07176
Primary Topic
Analytical Chemistry and Sensors
Type
article
Field-Weighted Citation Impact
0.00

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article

Sensor ToolKit (STK): Compact Multiplexing Potentiostat for Point-of-Care Applications

Pascal Blondeau, Jan Mitrovics, Francisco J. Andrade, A A Torres Acosta et al.
Analytical Chemistry
Analytical Chemistry and Sensors
article

Sensor ToolKit (STK): Compact Multiplexing Potentiostat for Point-of-Care Applications

Pascal Blondeau, Jan Mitrovics, Francisco J. Andrade, A A Torres Acosta, Moritz Kleinstraß, Alicia M. Maya, Simone Saporito
article en

Abstract

Embedded potentiostats have enabled the possibility of implementing electrochemical applications in a wide range of areas, from industry to healthcare. However, the optimization for either small size, low-cost devices, or sensor interfacing in existing platforms may lead to impractical outcomes. In this work, we propose Sensor ToolKit (STK), prototyped using off-the-shelf components and engineered to be a highly versatile, small, and low-cost platform of minimal complexity for the deployment of distributed IoT electrochemical sensors applications. The board implements an on-chip sequential input multiplexer that is especially suited for open-circuit potentiometry studies. The performance of the board was validated in potentiometric detection of potassium, hydrogen peroxide, glucose, and lactate, as well as self-current detection of hydrogen peroxide. Results show excellent analytical performance, comparable to that of benchtop instrumentation standards. The developed firmware and IoT framework enable the retrieval of sensor data wirelessly by a remote data server, which automates its real-time visualization using the Grafana web application, highlighting the potential of STK in distributed hyperconnected applications.

Analytical ChemistryVol. 98(8)
Krankenhaus vom Roten Kreuz (DE), Universitat Rovira i Virgili (ES)
Ministerio de Ciencia, Innovación y Universidades, European Commission, European Regional Development Fund, Agencia Estatal de Investigación
Industry, innovation and infrastructure
Openalex Percentile: Top 56%
Analytical Chemistry and Sensors
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Sensor ToolKit (STK): Compact Multiplexing Potentiostat for Point-of-Care Applications — Pascal Blondeau, Jan Mitrovics, et al. · Analytical Chemistry (2026) | TGRS Research Map | TGRS