Using silica nanoparticles to deliver antibiotics for treating Gram-positive bacterial infections in a 3D-bioprinted dermal model
The CFU count of the 3D-bioprinted human constructs samples treated with antibiotics was significantly lower than both the SiNP-treated and untreated samples. The results suggest that antibioticreleasing SiNPs can serve as a more efficient treatment for skin bacterial infections.
Authors
- Alexandre G. Brolo (ORCID: https://orcid.org/0000-0002-3162-0881)
- Claire Benwood
- Kali Scheck
- Stephanie Michelle Willerth (ORCID: https://orcid.org/0000-0002-1665-7723)
- Ariyan Suleman
- Ruchi Sharma
- Thiago Antonio Moretti de Andrade
Institutions
- University of Technology Sydney (AU)
- University of British Columbia (CA)
- Texas A&M University-Victoria (US)
- University of Victoria (CA)
- NĒRx BioSciences (United States) (US)
- Victoria University (AU)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2026-02-17
- DOI
- https://doi.org/10.3389/fbioe.2026.1737616
- Primary Topic
- 3D Printing in Biomedical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Canada Research Chairs
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Natural Sciences and Engineering Research Council of Canada