A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF SAPTHAVIMSHATI GUGGULU AND SOUBHAGYA VATI AFTER VIRECHANA IN PERIMENOPAUSAL SYNDROME

Perimenopausal syndrome is the transitional phase from reproductive to non-reproductive age characterized by somatic, psychological, and urogenital symptoms, which interfere with daily activities. In Ayurveda, this phase corresponds to Rajonivrutti, a Jara-kalaja Swabhavika avastha, where Pitta and Vata vriddhi lead to vitiation of Raja and involvement of Tama as a Manasika dosha. Objectives: To compare the efficacy of Sapthavimshathi Guggulu and Soubhagya Vati after Virechana in Perimenopausal syndrome. To evaluate the efficacy of Saptavimshathi Guggulu after Virechana in Perimenopausal syndrome. To evaluate the efficacy of Soubhagya Vati after Virechana in Perimenopausal syndrome. Materials and Methods: Total 40 subjects with 20 in each group. The interventions were as follows, Group A Virecana followed by Sapthavimshati guggulu as Shamanoushadhi. Group B Virecana followed by Soubhagya vati as Shamanoushadhi in the management of Perimenopausal syndrome. The data was collected on 0th day, after samsarjana krama and after the completion of follow-up period i.e. on 30th day. Results: Both the groups showed improvement from pretest to post-test. Group A demonstrated an overall improvement of 37.45% at mid-test and 66.50% at post-test, while Group B showed comparatively higher improvement of 40.16% at mid-test and 88.86% at post-test. Thus, Soubhagya Vati administered after Virechana was more effective than Sapthavimshati Guggulu in reducing Perimenopausal symptoms.