Development and validation of a clinical prediction model for first fall in early Parkinson’s disease: a study of two fall-naive cohorts

A history of falls is not necessary to predict the first fall in early PD. Our externally validated model, based on five easily ascertainable clinical factors, provides a practical tool for early risk stratification and can help guide individualized preventive strategies to delay or prevent initial falls in this vulnerable population.

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Publication Details

Journal
Frontiers in Aging Neuroscience
Published
2026-02-17
DOI
https://doi.org/10.3389/fnagi.2026.1735524
Primary Topic
Balance, Gait, and Falls Prevention
Type
article
Field-Weighted Citation Impact
0.00

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article

Development and validation of a clinical prediction model for first fall in early Parkinson’s disease: a study of two fall-naive cohorts

YunYun Zhang, Xueyi Han, Yunzhe Tang, Qingliang Tao et al.
Frontiers in Aging Neuroscience
Balance, Gait, and Falls Prevention
article

Development and validation of a clinical prediction model for first fall in early Parkinson’s disease: a study of two fall-naive cohorts

YunYun Zhang, Xueyi Han, Yunzhe Tang, Qingliang Tao, Zijun Wei, Jiyuan Hu, Yu Wang, Hongping Zhao
article en

Abstract

A history of falls is not necessary to predict the first fall in early PD. Our externally validated model, based on five easily ascertainable clinical factors, provides a practical tool for early risk stratification and can help guide individualized preventive strategies to delay or prevent initial falls in this vulnerable population.

Frontiers in Aging NeuroscienceVol. 18
Shanghai University of Traditional Chinese Medicine (CN), Yueyang Hospital (CN)
Bristol-Myers Squibb, Biogen, Celgene, Science and Technology Commission of Shanghai Municipality, Allergan, Avid Radiopharmaceuticals
Reduced inequalities, Peace, Justice and strong institutions
Openalex Percentile: Top 55%
Balance, Gait, and Falls Prevention
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