Single-cell systems network and machine learning dissection of ferroptosis in recurrent glioblastoma highlights astrocytic ZFP36 as a therapeutic hub for network medicine repurposing
The findings of this study suggest that modulating ferroptosis suppressor ZFP36 could promote cell death in rGBM via the ferroptosis pathway.
Authors
- Manoj Girish (ORCID: https://orcid.org/0000-0003-4610-5521)
- Mahima Kishinani
- Swati Sinha (ORCID: https://orcid.org/0000-0003-0795-8230)
- Sainitin Donakonda
Institutions
- TUM Klinikum (DE)
- M S Ramaiah University of Applied Sciences (IN)
Publication Details
- Journal
- European Journal of Cancer
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1016/j.ejca.2026.116591
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00