Effect of Hyperbaric Oxygen Therapy on Early MRI-Based Graft Healing Following ACL Reconstruction With Hamstring Autografts
In this pilot study, adjuvant HBOT following ACLR was associated with significantly improved signs of graft maturation and integration, as evidenced by lower graft signal intensity and interface signal on MRI at 4 months, suggesting accelerated early healing. These findings may help refine strategies to enhance early graft incorporation and support the development of rehabilitation protocols that optimize postoperative outcomes for patients undergoing ACLR.
Authors
- Camila Maftoum Cavalheiro (ORCID: https://orcid.org/0000-0002-5957-7424)
- Magno Santos Leite
- Marco Kawamura Demange
- Caio Oliveira D’Elia
- Alípio G. Ormond Filho
- Letícia R. Morimoto
- Chilan B. G. Leite
- Daniel Meirelles
Institutions
- Brigham and Women's Hospital (US)
- Instituto Vita (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
- Fleury S.A. (Brazil) (BR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- Orthopaedic Journal of Sports Medicine
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1177/23259671251413600
- Primary Topic
- Knee injuries and reconstruction techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00