Effect of early intensive physical therapy on NLRP3 inflammasome activation and muscle atrophy in critical illness myopathy (PT-NLRP3-CIM): a two-centre randomized open-label study protocol

Authors

Óscar Arellano-Pérez (ORCID: https://orcid.org/0000-0001-5596-1800)
Luan Américo-Da-Silva
Denisse Valladares-Ide (ORCID: https://orcid.org/0000-0001-7625-7978)
Felipe Castillo-Merino (ORCID: https://orcid.org/0000-0001-6382-8276)
Iván Hernández-Flores
Lilian Jara
Margot Navarrete-García
Federico Heredia-Wendt
Paola Llanos
Sebastián Ugarte-Ubiergo
Camila Pino-Figueroa

Institutions

Hospital Dipreca (CL)
University of O'Higgins (CL)
Center for Climate and Resilience Research (CL)
University of Chile (CL)

Publication Details

Journal: Trials
Published: 2026-02-18
DOI: https://doi.org/10.1186/s13063-026-09536-3
Primary Topic: Intensive Care Unit Cognitive Disorders
Type: article
Field-Weighted Citation Impact: 0.00

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article

Effect of early intensive physical therapy on NLRP3 inflammasome activation and muscle atrophy in critical illness myopathy (PT-NLRP3-CIM): a two-centre randomized open-label study protocol

Óscar Arellano-Pérez, Luan Américo-Da-Silva, Denisse Valladares-Ide, Felipe Castillo-Merino et al.

Feb 18, 2026

Trials

Intensive Care Unit Cognitive Disorders

article

Effect of early intensive physical therapy on NLRP3 inflammasome activation and muscle atrophy in critical illness myopathy (PT-NLRP3-CIM): a two-centre randomized open-label study protocol

Óscar Arellano-Pérez, Luan Américo-Da-Silva, Denisse Valladares-Ide, Felipe Castillo-Merino, Iván Hernández-Flores, Lilian Jara, Margot Navarrete-García, Federico Heredia-Wendt, Paola Llanos, Sebastián Ugarte-Ubiergo, Camila Pino-Figueroa

February 18, 2026article en

Abstract

No abstract available for this paper.

TrialsVol. 27(1)

Hospital Dipreca (CL), University of O'Higgins (CL), Center for Climate and Resilience Research (CL), University of Chile (CL)

Openalex Percentile: Top 54%

Intensive Care Unit Cognitive Disorders

DOI Open Access PDF OpenAlex

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