Glucagon-Like Peptide 1 Receptor Agonists and Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients With Type 2 Diabetes

GLP-1 RAs were associated with an increased 1-year risk of NAION compared with DPP-4 inhibitors among adults with type 2 diabetes, particularly in younger patients, men, ever-smokers, and patients with a marked hemoglobin A1c reduction.

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Publication Details

Journal
Diabetes Care
Published
2026-02-17
DOI
https://doi.org/10.2337/dc25-2577
Primary Topic
Intraoperative Neuromonitoring and Anesthetic Effects
Type
article
Field-Weighted Citation Impact
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article

Glucagon-Like Peptide 1 Receptor Agonists and Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients With Type 2 Diabetes

Yunha Noh, I. Ben Ghezala, Samy Suissa, Laurent Azoulay et al.
Diabetes Care
Intraoperative Neuromonitoring and Anesthetic Effects
article

Glucagon-Like Peptide 1 Receptor Agonists and Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients With Type 2 Diabetes

Yunha Noh, I. Ben Ghezala, Samy Suissa, Laurent Azoulay, Oriana H.Y. Yu, Hui Yin
article en

Abstract

GLP-1 RAs were associated with an increased 1-year risk of NAION compared with DPP-4 inhibitors among adults with type 2 diabetes, particularly in younger patients, men, ever-smokers, and patients with a marked hemoglobin A1c reduction.

Diabetes Care
Chonnam National University (KR), Inserm (FR), McGill University Health Centre (CA), Jewish General Hospital (CA), Maison des Sciences sociales et des Humanités de Dijon (FR), McGill University (CA)
Good health and well-being
Openalex Percentile: Top 53%
Intraoperative Neuromonitoring and Anesthetic Effects
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