MedPTQ: a practical pipeline for real post-training quantization in 3D medical image segmentation

We have introduced MedPTQ, a real post-training quantization pipeline that delivers INT8 inference for SOTA 3D artificial intelligence (AI) models in medical imaging segmentation. MedPTQ effectively reduces real-world model size, computational requirements, and inference latency without compromising segmentation accuracy on modern GPUs, as evidenced by mDSC comparable to full-precision baselines. We validate MedPTQ across a diverse set of AI architectures, ranging from convolutional-neural-network-based to transformer-based models, and a wide variety of medical imaging datasets. These datasets are collected from multiple hospitals with distinct imaging protocols, cover different body regions (such as the brain, abdomen, or full body), and include multiple imaging modalities [computed tomography (CT) and magnetic resonance imaging (MRI)]. Collectively, these results highlight our MedPTQ's strong generalizability and adaptability for a broad spectrum of medical imaging tasks.

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Publication Details

Journal
Journal of Medical Imaging
Published
2026-02-17
DOI
https://doi.org/10.1117/1.jmi.13.1.014006
Primary Topic
Advanced Neural Network Applications
Type
article
Field-Weighted Citation Impact
0.00

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MedPTQ: a practical pipeline for real post-training quantization in 3D medical image segmentation

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MedPTQ: a practical pipeline for real post-training quantization in 3D medical image segmentation

Ritchie Zhao, Tianyuan Yao, Junchao Zhu, Yucheng Tang, Chongyu Qu, Yuankai Z Huo, Bennett A. Landman, Ye Yu, Bin Liu
article en

Abstract

We have introduced MedPTQ, a real post-training quantization pipeline that delivers INT8 inference for SOTA 3D artificial intelligence (AI) models in medical imaging segmentation. MedPTQ effectively reduces real-world model size, computational requirements, and inference latency without compromising segmentation accuracy on modern GPUs, as evidenced by mDSC comparable to full-precision baselines. We validate MedPTQ across a diverse set of AI architectures, ranging from convolutional-neural-network-based to transformer-based models, and a wide variety of medical imaging datasets. These datasets are collected from multiple hospitals with distinct imaging protocols, cover different body regions (such as the brain, abdomen, or full body), and include multiple imaging modalities [computed tomography (CT) and magnetic resonance imaging (MRI)]. Collectively, these results highlight our MedPTQ's strong generalizability and adaptability for a broad spectrum of medical imaging tasks.

Journal of Medical ImagingVol. 13(01)
Vanderbilt University (US), Nvidia (United States) (US)
National Science Foundation, U.S. Department of Defense, Vanderbilt University, Nvidia, National Institutes of Health
Partnerships for the goals
Openalex Percentile: Top 54%
Advanced Neural Network Applications
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