Dose–response analysis of valproate, levetiracetam and lamotrigine in idiopathic generalized epilepsy
Both valproate and levetiracetam show a clear dose-response in IGE. In contrast, increasing lamotrigine doses above 400 mg/day did not confer additional effect on seizures.
Authors
- Joanna Gesche (ORCID: https://orcid.org/0000-0002-0546-4619)
- Amine Abdullah-Roskjær
- Guido Rubboli
- Christoph P. Beier
Institutions
- University of Southern Denmark (DK)
- Odense University Hospital (DK)
- Epilepsy Action (GB)
Publication Details
- Journal
- Epilepsy & Behavior
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1016/j.yebeh.2026.110940
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jascha Fonden
- Lundbeckfonden
- Odense Universitetshospital
- H. Lundbeck A/S