Histatin-5 Improves In Vivo Corneal Wound Healing and Immunohistochemical Neovascular Markers After Acute Alkali Injury

Topical Histatin-5 promotes epithelial regeneration and suppresses inflammation-driven corneal neovascularization following alkali injury, suggesting Hst5 as a novel, biologically-derived treatment to accelerate corneal healing and prevent vision loss after chemical burns.

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Publication Details

Journal
Translational Vision Science & Technology
Published
2026-02-17
DOI
https://doi.org/10.1167/tvst.15.2.20
Primary Topic
Corneal Surgery and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Histatin-5 Improves In Vivo Corneal Wound Healing and Immunohistochemical Neovascular Markers After Acute Alkali Injury

Vinay K. Aakalu, Deepak Shukla, Dhara Shah, Christian Reinhardt et al.
Translational Vision Science & Technology
Corneal Surgery and Treatments
article

Histatin-5 Improves In Vivo Corneal Wound Healing and Immunohistochemical Neovascular Markers After Acute Alkali Injury

Vinay K. Aakalu, Deepak Shukla, Dhara Shah, Christian Reinhardt, Sang Min Lee, Manoj Chaudhary, Kyuyeon Han, Kyung-No Son, Joshua Ong
article en

Abstract

Topical Histatin-5 promotes epithelial regeneration and suppresses inflammation-driven corneal neovascularization following alkali injury, suggesting Hst5 as a novel, biologically-derived treatment to accelerate corneal healing and prevent vision loss after chemical burns.

Translational Vision Science & TechnologyVol. 15(2)
University of Michigan (US), University of Illinois Chicago (US), University of Chicago (US)
Good health and well-being
Openalex Percentile: Top 53%
Corneal Surgery and Treatments
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