Evaluation of the diagnostic accuracy of two esophageal biopsy sites compared to three in histological follow-up of eosinophilic esophagitis – A multicentric study
In EoE follow-up, two-site (distal+proximal) biopsies provide classification nearly equivalent to three-site sampling, with only a 2 % miss rate for active disease when the middle site is omitted. This approach may reduce procedure time, patient discomfort, and costs while maintaining excellent diagnostic performance.
Authors
- Roberto Penagini (ORCID: https://orcid.org/0000-0001-6918-9479)
- Giovanni Aldinio
- Andrea Sorge (ORCID: https://orcid.org/0000-0002-0285-9949)
- Daria Maniero (ORCID: https://orcid.org/0000-0003-2468-7292)
- Beatrice Marinoni (ORCID: https://orcid.org/0000-0002-8891-8996)
- Luca Mastracci (ORCID: https://orcid.org/0000-0003-0193-5281)
- Manuele Furnari (ORCID: https://orcid.org/0000-0001-6424-079X)
- Nicola De Bortoli
- Elisa Marabotto
- A Pasta
- Giorgia Bodini
- Federica Grillo
- Marina Coletta
- Tommaso Pessarelli
- Pierfrancesco Visaggi
- Maurizio Vecchi
- Edoardo Vincenzo Savarino
- Francesco Calabrese
Institutions
- University of Pisa (IT)
- University of Padua (IT)
- University of Milan (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Ospedale Policlinico San Martino (IT)
Publication Details
- Journal
- Digestive and Liver Disease
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1016/j.dld.2026.01.219
- Primary Topic
- Eosinophilic Esophagitis
- Type
- article
- Field-Weighted Citation Impact
- 0.00