FENDRR-mediated regulation of osteoclast differentiation through the miRNA-129-5p/P2X7R axis
These findings suggest that FENDRR plays a significant role in the pathophysiology of osteoarthritis by promoting osteoclast development and activation, thereby exacerbating inflammatory cascades.
Authors
- Huaxing Zhang (ORCID: https://orcid.org/0000-0002-7060-0808)
- Yujie Jin
- Fei Wang
- Jia Chen
Institutions
- Hebei Medical University (CN)
- Third Hospital of Hebei Medical University (CN)
- Hebei General Hospital (CN)
- First Affiliated Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1186/s13018-026-06715-5
- Primary Topic
- Adenosine and Purinergic Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00