An open-source motion platform that replicates time synchronised internal and external patient motion for real-time image-guided radiotherapy

Real-time Image-guided Radiotherapy (IGRT) technologies aim to track intra-fractional tumour motion during delivery of high radiation doses to tumours. For the development and safe implementation of real-time IGRT technologies into the clinic, there is a need for robust and repeatable quality assurance (QA) devices. Motivated by this need, this work presents the development and characterisation of a novel time-synchronised motion platform designed for QA purposes of real-time IGRT technologies that perform combined internal and external patient motion monitoring. The Internal-External Robotic Actuator (IntERAct) QA device was developed to integrate a 6-degree-of-freedom (6DoF) robotic arm with a 1-degree-of-freedom (1DoF) motion actuator, which replicate 6DoF internal tumour and 1DoF external surface movements, respectively. The IntERAct device was validated by performing tests which replicated patient-measured lung and liver motion traces on the 6DoF and 1DoF platforms. The device synchronised the internal and external motions to within 0.1 s with under two-millimetre geometric accuracy. The full details of the IntERAct device have been compiled into an open-source repository on GitHub for the medical physics community to use: https://github.com/Image-X-Institute/IntERAct .

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Publication Details

Journal
Physical and Engineering Sciences in Medicine
Published
2026-02-17
DOI
https://doi.org/10.1007/s13246-026-01710-w
Primary Topic
Advanced Radiotherapy Techniques
Type
article
Field-Weighted Citation Impact
0.00

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article

An open-source motion platform that replicates time synchronised internal and external patient motion for real-time image-guided radiotherapy

Fang Jin, Paul Keall, C. Sengupta, Jonathan Hindmarsh et al.
Physical and Engineering Sciences in Medicine
Advanced Radiotherapy Techniques
article

An open-source motion platform that replicates time synchronised internal and external patient motion for real-time image-guided radiotherapy

Fang Jin, Paul Keall, C. Sengupta, Jonathan Hindmarsh, Daniel Mason, Julia V. Johnson, Alicja Kaczynska, Maegan Stewart, Abbas Zahr, Ann Yan, William Nixon, Chris Kuban
article en

Abstract

Real-time Image-guided Radiotherapy (IGRT) technologies aim to track intra-fractional tumour motion during delivery of high radiation doses to tumours. For the development and safe implementation of real-time IGRT technologies into the clinic, there is a need for robust and repeatable quality assurance (QA) devices. Motivated by this need, this work presents the development and characterisation of a novel time-synchronised motion platform designed for QA purposes of real-time IGRT technologies that perform combined internal and external patient motion monitoring. The Internal-External Robotic Actuator (IntERAct) QA device was developed to integrate a 6-degree-of-freedom (6DoF) robotic arm with a 1-degree-of-freedom (1DoF) motion actuator, which replicate 6DoF internal tumour and 1DoF external surface movements, respectively. The IntERAct device was validated by performing tests which replicated patient-measured lung and liver motion traces on the 6DoF and 1DoF platforms. The device synchronised the internal and external motions to within 0.1 s with under two-millimetre geometric accuracy. The full details of the IntERAct device have been compiled into an open-source repository on GitHub for the medical physics community to use: https://github.com/Image-X-Institute/IntERAct .

Physical and Engineering Sciences in Medicine
The University of Sydney (AU), Royal North Shore Hospital (AU), Nepean Hospital (AU)
National Cancer Research Institute, Australian Government
Openalex Percentile: Top 47%
Advanced Radiotherapy Techniques
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