Palmitic acid aggravates airway inflammation in asthma through induction of chemokines expression and metabolomic changes in epithelial cells
our study demonstrated elevated PA exacerbates airway inflammation in asthma by inducing neutrophil chemokine expression and metabolic reprogramming in airway epithelial cells, providing novel insights into the pathophysiology of metabolically dysregulated asthma.
Authors
- Cuiting Shan
- Xiayi Miao (ORCID: https://orcid.org/0009-0006-2883-9037)
- Zhenhua Ni
- Jialu Ma
- Qingge Chen (ORCID: https://orcid.org/0000-0003-4015-8470)
- Wenguan Li
- Xiongbiao Wang
- Yue Wu
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Longhua Hospital Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai Traditional Chinese Medicine Hospital (CN)
- Central Hospital of Putuo District (CN)
Publication Details
- Journal
- Allergology International
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.alit.2026.01.004
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00