Transanal irrigation for low anterior resection syndrome: a systematic review and narrative synthesis with emphasis on nurse-led implementation
TAI shows promise an effective and well-tolerated intervention for LARS, particularly when delivered through structured, nurse-supported protocols. However, the limited number and heterogeneity of available studies, combined with small sample sizes (total N=332) and short follow-up durations (median 4 months), highlight the need for large, multicenter randomized trials with extended follow-up (≥12 months) to confirm long-term effectiveness and establish standardized implementation strategies.
Authors
- Daniele Napolitano (ORCID: https://orcid.org/0000-0003-2481-5354)
- Diego Lopane (ORCID: https://orcid.org/0000-0002-4822-5001)
- Mauro Parozzi (ORCID: https://orcid.org/0000-0003-4164-2790)
- Elena Papini
- Filippo Maria Bianchi (ORCID: https://orcid.org/0000-0002-7145-3846)
- Alessandra Dacomi (ORCID: https://orcid.org/0000-0001-9405-3709)
- Simone Cosmai (ORCID: https://orcid.org/0009-0000-5101-0207)
- Sarah Scollo
- Bianca FIDATO
- Beatrice MAZZOLENI
- Alessio LO CASCIO
- Daniela CATTANI
- Stefano MANCIN
- Alessio SCARPA
Institutions
- University of Rome Tor Vergata (IT)
- Humanitas University (IT)
- Agostino Gemelli University Polyclinic (IT)
- IRCCS Humanitas Research Hospital (IT)
- La Maddalena (IT)
Publication Details
- Journal
- Minerva Gastroenterology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.23736/s2724-5985.26.04075-1
- Primary Topic
- Anorectal Disease Treatments and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00