Campylobacter jejuni Enteritis Mimicking Mechanical Small Bowel Obstruction

In this case, we present an 84-year-old patient admitted for small bowel obstruction (SBO) with radiographic evidence of a clear transition point in the proximal small bowel on a computed tomography (CT) scan. Given his prior history of hemicolectomy, surgical adhesions were suspected as the likely cause. After several days of poor response to supportive treatment, he developed significant secretory diarrhea with stool samples positive for <i>Campylobacter jejuni.</i> In rare cases, <i>C. jejuni</i> enteritis can mimic SBO. We suggest that his SBO initially resembled mechanical obstruction on imaging due to significant bacterial induced circumferential bowel thickening and edema as opposed to the usual pseudo-obstruction from bacterial activated pro-inflammatory mediators, which disrupt intestinal motility. His obstruction resolved with a course of azithromycin antibiotics and conservative measures.

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Publication Details

Journal
Cureus
Published
2026-02-16
DOI
https://doi.org/10.7759/cureus.103748
Primary Topic
Salmonella and Campylobacter epidemiology
Type
article
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article

Campylobacter jejuni Enteritis Mimicking Mechanical Small Bowel Obstruction

Sina Shafiei, Atefeh Kalantary, Mohammad S. Alghussein, Gholamreza Badiee et al.
Cureus
Salmonella and Campylobacter epidemiology
article

Campylobacter jejuni Enteritis Mimicking Mechanical Small Bowel Obstruction

Sina Shafiei, Atefeh Kalantary, Mohammad S. Alghussein, Gholamreza Badiee, Michael E Lazarus, Amir H Talebi
article en

Abstract

In this case, we present an 84-year-old patient admitted for small bowel obstruction (SBO) with radiographic evidence of a clear transition point in the proximal small bowel on a computed tomography (CT) scan. Given his prior history of hemicolectomy, surgical adhesions were suspected as the likely cause. After several days of poor response to supportive treatment, he developed significant secretory diarrhea with stool samples positive for <i>Campylobacter jejuni.</i> In rare cases, <i>C. jejuni</i> enteritis can mimic SBO. We suggest that his SBO initially resembled mechanical obstruction on imaging due to significant bacterial induced circumferential bowel thickening and edema as opposed to the usual pseudo-obstruction from bacterial activated pro-inflammatory mediators, which disrupt intestinal motility. His obstruction resolved with a course of azithromycin antibiotics and conservative measures.

CureusVol. 18(2)
University of California, Los Angeles (US), Los Robles Hospital & Medical Center (US)
No poverty
Openalex Percentile: Top 52%
Salmonella and Campylobacter epidemiology
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Campylobacter jejuni Enteritis Mimicking Mechanical Small Bowel Obstruction — Sina Shafiei, Atefeh Kalantary, et al. · Cureus (2026) | TGRS Research Map | TGRS