Lactylation of BCAT2-K377 Contributes to the Progression of Severe Preeclampsia

Our findings emphasized the role of nonhistone lactylation in sPE pathogenesis. Targeting BCAT2-K377la may serve as a potential intervention strategy for sPE.

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Publication Details

Journal
Hypertension
Published
2026-02-17
DOI
https://doi.org/10.1161/hypertensionaha.125.25378
Primary Topic
Pregnancy and preeclampsia studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Lactylation of BCAT2-K377 Contributes to the Progression of Severe Preeclampsia

Yong Zhang, Liming Yuan, Yangxue Yin, Qin Xu et al.
Hypertension
Pregnancy and preeclampsia studies
article

Lactylation of BCAT2-K377 Contributes to the Progression of Severe Preeclampsia

Yong Zhang, Liming Yuan, Yangxue Yin, Qin Xu, Yanfang Li, Yanping Zhang, Lingyun Liao, Yanyun Wang, Rong Zhou
article en

Abstract

Our findings emphasized the role of nonhistone lactylation in sPE pathogenesis. Targeting BCAT2-K377la may serve as a potential intervention strategy for sPE.

Hypertension
Sichuan University (CN), Sichuan Agricultural University (CN)
Good health and well-being
Openalex Percentile: Top 55%
Pregnancy and preeclampsia studies
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