Safety and Effectiveness of Low-Dose Valganciclovir Prophylaxis in Cytomegalovirus Seropositive Lung Transplant Recipients
In CMV-seropositive adult LTx recipients without induction therapy, low-dose VGCV prophylaxis was as safe and effective as standard-dose prophylaxis and was associated with superior CLAD-free survival. Future randomized clinical trial is warranted.
Authors
- J. Ristikankare
- Kishor Dhaygude (ORCID: https://orcid.org/0000-0003-4499-6180)
- Elina Heliövaara
- Karl Lemström
- Antti I. Nykänen (ORCID: https://orcid.org/0000-0003-3027-2309)
- Simo Syrjälä
- Rasmus A J Lehikoinen
- Jussi Tikkanen
Institutions
- University of Helsinki (FI)
- Helsinki University Hospital (FI)
Publication Details
- Journal
- European Journal of Cardio-Thoracic Surgery
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1093/ejcts/ezag095
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00