Oral Necrotizing Ulcerations in Acute Leukemia Patients: Clinical Characteristics, Integrated Management, and Favorable Outcomes – A Case Series

Oral Necrotizing Ulcerations, including NUG, NUP, and NUS, represent significant clinical manifestations of acute leukemia, reflecting the underlying immunosuppression, hematologic abnormalities, and oral microbial dysbiosis inherent to the disease. Early recognition of characteristic clinical features, followed by integrated local oral management and close coordination with systemic medical care, can lead to favorable healing outcomes despite profound hematologic compromise.

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Publication Details

Journal
International Medical Case Reports Journal
Published
2026-02-01
DOI
https://doi.org/10.2147/imcrj.s570294
Primary Topic
Oral health in cancer treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Oral Necrotizing Ulcerations in Acute Leukemia Patients: Clinical Characteristics, Integrated Management, and Favorable Outcomes – A Case Series

Nuri Fitriasari, Fajar Priandhika, Wahyu Hidayat
International Medical Case Reports Journal
Oral health in cancer treatment
article

Oral Necrotizing Ulcerations in Acute Leukemia Patients: Clinical Characteristics, Integrated Management, and Favorable Outcomes – A Case Series

Nuri Fitriasari, Fajar Priandhika, Wahyu Hidayat
article en

Abstract

Oral Necrotizing Ulcerations, including NUG, NUP, and NUS, represent significant clinical manifestations of acute leukemia, reflecting the underlying immunosuppression, hematologic abnormalities, and oral microbial dysbiosis inherent to the disease. Early recognition of characteristic clinical features, followed by integrated local oral management and close coordination with systemic medical care, can lead to favorable healing outcomes despite profound hematologic compromise.

International Medical Case Reports JournalVol. Volume 19
Dr. Hasan Sadikin General Hospital (ID), Padjadjaran University (ID)
Ministrstvo za visoko šolstvo, znanost in tehnologijo, Lembaga Pengelola Dana Pendidikan, Universitas Padjadjaran
Good health and well-being
Openalex Percentile: Top 53%
Oral health in cancer treatment
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