Oral Necrotizing Ulcerations in Acute Leukemia Patients: Clinical Characteristics, Integrated Management, and Favorable Outcomes – A Case Series
Oral Necrotizing Ulcerations, including NUG, NUP, and NUS, represent significant clinical manifestations of acute leukemia, reflecting the underlying immunosuppression, hematologic abnormalities, and oral microbial dysbiosis inherent to the disease. Early recognition of characteristic clinical features, followed by integrated local oral management and close coordination with systemic medical care, can lead to favorable healing outcomes despite profound hematologic compromise.
Authors
- Nuri Fitriasari (ORCID: https://orcid.org/0000-0002-6720-285X)
- Fajar Priandhika
- Wahyu Hidayat
Institutions
- Dr. Hasan Sadikin General Hospital (ID)
- Padjadjaran University (ID)
Publication Details
- Journal
- International Medical Case Reports Journal
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/imcrj.s570294
- Primary Topic
- Oral health in cancer treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministrstvo za visoko šolstvo, znanost in tehnologijo
- Lembaga Pengelola Dana Pendidikan
- Universitas Padjadjaran