Lam Employment Absence and Productivity Scale (LEAPS): Analysis of the minimal clinically important difference (MCID) in patients with major depressive disorder using data from the CAN-BIND-1 study

Establishing an MCID is important for determining clinically relevant change in the LEAPS, both for treatment studies and for individual patients in clinical care. For clinical use, the proposed MCID is 3 points for the LEAPS total score and 2 points for the LEAPS productivity subscale score.

Authors

Institutions

Publication Details

Journal
Journal of Affective Disorders
Published
2026-02-17
DOI
https://doi.org/10.1016/j.jad.2026.121451
Primary Topic
Treatment of Major Depression
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Lam Employment Absence and Productivity Scale (LEAPS): Analysis of the minimal clinically important difference (MCID) in patients with major depressive disorder using data from the CAN-BIND-1 study

Victor W. Li, S. H. Kennedy, RUDOLF UHER, Stefanie Hassel et al.
Journal of Affective Disorders
Treatment of Major Depression
article

Lam Employment Absence and Productivity Scale (LEAPS): Analysis of the minimal clinically important difference (MCID) in patients with major depressive disorder using data from the CAN-BIND-1 study

Victor W. Li, S. H. Kennedy, RUDOLF UHER, Stefanie Hassel, Benicio N. Frey, Keith Ho, Roumen Milev, Claudio N. Soares, Susan Rotzinger, Raymond W. Lam, Valerie H. Taylor, Trisha Chakrabarty, Sagar V. Parikh, Shiny Sachdeva, Daniel J. Müller
article en

Abstract

Establishing an MCID is important for determining clinically relevant change in the LEAPS, both for treatment studies and for individual patients in clinical care. For clinical use, the proposed MCID is 3 points for the LEAPS total score and 2 points for the LEAPS productivity subscale score.

Journal of Affective DisordersVol. 403
University of British Columbia Hospital (CA), Dalhousie University (CA), University of British Columbia (CA), University of Calgary (CA), University of Toronto (CA), Queen's University (CA), University of Michigan (US), McMaster University (CA)
Decent work and economic growth
Openalex Percentile: Top 53%
Treatment of Major Depression
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Lam Employment Absence and Productivity Scale (LEAPS): Analysis of the minimal clinically important difference (MCID) in patients with major depressive disorder using data from the CAN-BIND-1 study — Victor W. Li, S. H. Kennedy, et al. · Journal of Affective Disorders (2026) | TGRS Research Map | TGRS