Brown Tumor in a Patient With End-Stage Renal Disease: A Case Report of Secondary Hyperparathyroidism Complications

The development of a brown tumor is a rare complication of secondary hyperparathyroidism, particularly in patients with chronic kidney disease. Despite advances in the treatment and management of secondary hyperparathyroidism, these tumors can still occur. We report the case of a 29-year-old man with end-stage renal disease treated with hemodialysis, who developed a brown tumor in the ribs. Despite medical treatment including calcium and vitamin D supplementation, and multiple parathyroidectomies, imaging revealed an expansive and sclerotic costal lesion, confirmed as a brown tumor. Diagnosis is based on clinical, biological, and radiological evaluations. Treatments aim to reduce parathyroid hormone (PTH) levels and correct metabolic abnormalities, with parathyroidectomy as an option in cases of medical treatment failure.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2026-02-17
DOI
https://doi.org/10.7759/cureus.103787
Primary Topic
Parathyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Brown Tumor in a Patient With End-Stage Renal Disease: A Case Report of Secondary Hyperparathyroidism Complications

Zakaria Mimouni, Rachid Marouf, Ahdadi Ahmed, Hamraoui Salima et al.
Cureus
Parathyroid Disorders and Treatments
article

Brown Tumor in a Patient With End-Stage Renal Disease: A Case Report of Secondary Hyperparathyroidism Complications

Zakaria Mimouni, Rachid Marouf, Ahdadi Ahmed, Hamraoui Salima, Assadiki Akram
article en

Abstract

The development of a brown tumor is a rare complication of secondary hyperparathyroidism, particularly in patients with chronic kidney disease. Despite advances in the treatment and management of secondary hyperparathyroidism, these tumors can still occur. We report the case of a 29-year-old man with end-stage renal disease treated with hemodialysis, who developed a brown tumor in the ribs. Despite medical treatment including calcium and vitamin D supplementation, and multiple parathyroidectomies, imaging revealed an expansive and sclerotic costal lesion, confirmed as a brown tumor. Diagnosis is based on clinical, biological, and radiological evaluations. Treatments aim to reduce parathyroid hormone (PTH) levels and correct metabolic abnormalities, with parathyroidectomy as an option in cases of medical treatment failure.

CureusVol. 18(2)
Mohamed I University (MA)
Good health and well-being
Openalex Percentile: Top 59%
Parathyroid Disorders and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.