Clinical study on the application of biological mesh and synthetic mesh in laparoscopic inguinal hernia repair

To evaluate the efficacy and safety of biological mesh in laparoscopic inguinal hernia repair. A retrospective analysis was conducted on 200 patients who underwent laparoscopic transabdominal preperitoneal repair (TAPP) between March 2019 and March 2022. Patients were divided into Group A (n = 100), repaired with acellular matrix biological mesh, and Group B (n = 100), repaired with polypropylene mesh. Follow-ups were performed at 1, 3, 6 months, 1 year, and 3 years postoperatively. Outcome measures included operation time, intraoperative blood loss, postoperative hospital stay, recurrence, infection, seroma, foreign body sensation, and chronic pain. No significant differences were observed between the two groups in operation time, intraoperative blood loss, postoperative hospital stay, recurrence, infection, seroma, or chronic pain (P > 0.05). However, the incidence of foreign body sensation was significantly lower in the Group A (P < 0.05). The acellular matrix biological mesh is safe and effective in the treatment of inguinal hernia, and can reduce the incidence of postoperative foreign body sensation at the same time, providing a new choice for laparoscopic inguinal hernia repair.