Plummer–vinson syndrome presenting with dysphagia in a pediatric patient: A rare case report and review of management

Plummer-Vinson syndrome (PVS), also known as Paterson-Brown-Kelly syndrome, is a rare disorder marked by iron deficiency anemia, difficulty swallowing, and upper esophageal webs. It predominantly affects middle-aged women and is rarely observed in children. Although the precise mechanisms remain unclear, iron deficiency is frequently implicated as the underlying cause. This report details an unusual pediatric case of PVS in an eight year-old girl with longstanding anemia and progressive dysphagia. Laboratory studies confirmed microcytic hypochromic anemia, and an upper GI Series suggested a proximal esophageal web. Initial treatment with oral iron showed no improvement. Eventually, an esophagogastroduodenoscopy confirmed the presence of a web near the upper esophageal sphincter. Endoscopic dilation was performed successfully, allowing for resolution of symptoms.

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Publication Details

Journal
Global Pediatrics
Published
2026-02-17
DOI
https://doi.org/10.1016/j.gpeds.2026.100326
Primary Topic
Esophageal and GI Pathology
Type
article
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article

Plummer–vinson syndrome presenting with dysphagia in a pediatric patient: A rare case report and review of management

Mohamed Issak Adan, Abdikarin Ahmed Mohamed, Yahye A. Mohamud Shole
Global Pediatrics
Esophageal and GI Pathology
article

Plummer–vinson syndrome presenting with dysphagia in a pediatric patient: A rare case report and review of management

Mohamed Issak Adan, Abdikarin Ahmed Mohamed, Yahye A. Mohamud Shole
article en

Abstract

Plummer-Vinson syndrome (PVS), also known as Paterson-Brown-Kelly syndrome, is a rare disorder marked by iron deficiency anemia, difficulty swallowing, and upper esophageal webs. It predominantly affects middle-aged women and is rarely observed in children. Although the precise mechanisms remain unclear, iron deficiency is frequently implicated as the underlying cause. This report details an unusual pediatric case of PVS in an eight year-old girl with longstanding anemia and progressive dysphagia. Laboratory studies confirmed microcytic hypochromic anemia, and an upper GI Series suggested a proximal esophageal web. Initial treatment with oral iron showed no improvement. Eventually, an esophagogastroduodenoscopy confirmed the presence of a web near the upper esophageal sphincter. Endoscopic dilation was performed successfully, allowing for resolution of symptoms.

Global PediatricsVol. 16
Paragon International University (KH), University of Somalia (SO), Institute of Child Health (IN)
Good health and well-being
Openalex Percentile: Top 53%
Esophageal and GI Pathology
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Plummer–vinson syndrome presenting with dysphagia in a pediatric patient: A rare case report and review of management — Mohamed Issak Adan, Abdikarin Ahmed Mohamed, et al. · Global Pediatrics (2026) | TGRS Research Map | TGRS