Fasting Plasma Glucose Mediates the Association Between the Atherogenic Index of Plasma and Depression in US Adults: A Study From NHANES 2005-2020

AIP is positively associated with depression, with FPG statistically explaining a significant portion of this association. These findings suggest a potential link between lipid metabolism, glucose homeostasis, and depression, highlighting AIP as a correlate that merits further investigation in the context of mental health.

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Publication Details

Journal
Endocrine Practice
Published
2026-02-01
DOI
https://doi.org/10.1016/j.eprac.2026.02.009
Primary Topic
Cardiac Health and Mental Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Fasting Plasma Glucose Mediates the Association Between the Atherogenic Index of Plasma and Depression in US Adults: A Study From NHANES 2005-2020

Zhu Chen, Tingting Hu, Jun Su, Ying Zhang
Endocrine Practice
Cardiac Health and Mental Health
article

Fasting Plasma Glucose Mediates the Association Between the Atherogenic Index of Plasma and Depression in US Adults: A Study From NHANES 2005-2020

Zhu Chen, Tingting Hu, Jun Su, Ying Zhang
article en

Abstract

AIP is positively associated with depression, with FPG statistically explaining a significant portion of this association. These findings suggest a potential link between lipid metabolism, glucose homeostasis, and depression, highlighting AIP as a correlate that merits further investigation in the context of mental health.

Endocrine Practice
Hangzhou Women’s Hospital (CN), Zhejiang Hospital (CN), Hangzhou Seventh Peoples Hospital (CN)
Good health and well-being
Openalex Percentile: Top 57%
Cardiac Health and Mental Health
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