Astrocytic PYGM attenuates tau pathology by promoting lactate‐mediated neuroprotection
Astrocytic PYGM supports neuronal health by sustaining lactate-mediated astrocyte-neuron metabolic coupling. Enhancing astrocytic glycogenolysis may be beneficial in tauopathies.
Authors
- Jing Cao (ORCID: https://orcid.org/0000-0003-3124-4780)
- Huihui Li (ORCID: https://orcid.org/0000-0001-6004-3086)
- Jian Meng (ORCID: https://orcid.org/0000-0002-6966-3326)
- Hong Luo
- Ziqian Tang
- Zhanxiang Wang
- Kun Li
- Yun‐wu Zhang
- Yong Wang
- Xian Zhang
Institutions
- Xiamen University (CN)
- First Affiliated Hospital of Xiamen University (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/alz.71202
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00