Multistage Electrocardiographic Profiling for Mental Stress-Induced Myocardial Ischemia in Women: A Prospective, Age-Matched Cohort Study in China
Multistage ECG analysis, particularly heart rate variability, captures electrophysiological signatures of mental stress-induced myocardial ischemia and enhances noninvasive detection. These findings support a paradigm shift from single-phase, ischemia-focused ECG interpretation to dynamic, multivariable assessment, providing a foundation for early identification and personalized risk stratification in women with nonobstructive coronary disease.
Authors
- Xiaoting Peng
- Yong Li (ORCID: https://orcid.org/0000-0003-4038-0493)
- Entao Liu (ORCID: https://orcid.org/0000-0002-0388-5540)
- Xueli Zhang (ORCID: https://orcid.org/0000-0002-7420-8125)
- Yilin Niu
- Hao Liang (ORCID: https://orcid.org/0000-0002-6851-8418)
- Lianting Hu
- Huixian Li
- Dantong Li
- Shuai Huang
- Qingshan Geng
- Huan Ma
- Chao Wu
Institutions
- Guangdong University of Technology (CN)
- Chinese University of Hong Kong (HK)
- Southern University of Science and Technology (CN)
- Stanley Medical Research Institute (US)
- Wuhan Children's Hospital (CN)
- Guangdong Academy of Medical Sciences (CN)
- Shenzhen Institutes of Advanced Technology (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
- South China University of Technology (CN)
Publication Details
- Journal
- Circulation Population Health and Outcomes
- Published
- 2026-02-16
- DOI
- https://doi.org/10.1161/circoutcomes.125.012750
- Citations
- 1
- Primary Topic
- ECG Monitoring and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 30.07