Putative sympathetic-predominant subtype in body-first Parkinson’s disease is associated with accelerated cognitive decline
These findings indicated that sympathetic-predominant body-first PD may be associated with a more rapid trajectory of cognitive decline, although the observed effect was modest and warrants cautious interpretation.
Authors
- Tianyu Hu
- Xining Liu
- Shiyu Li (ORCID: https://orcid.org/0000-0001-8420-9343)
- Zhiheng Xu
- J Wang
- Yilin Tang
- Chenqin Xu
- Chen Chen
- Xiaoniu Liang
- Xiuyuan Li
Institutions
- Huashan Hospital (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2026-02-16
- DOI
- https://doi.org/10.3389/fnagi.2026.1747748
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Science and Technology Major Project
- National Health Commission of the People's Republic of China