RNA Sequencing of Sepsis Patients Informs Tests to Quickly Diagnose Pathogens and Resistance
RNA sequencing from patients with sepsis can identify RNA from pathogens causing the infection. This is used to design PCR primers that identify patients with positive blood cultures. Translation of these primers to clinical microbiology machines will allow the diagnosis faster than blood culture.
Authors
- Antonio Ayala (ORCID: https://orcid.org/0000-0001-9711-3711)
- Kwesi K Lillard
- Jaewook Shin (ORCID: https://orcid.org/0000-0003-0445-546X)
- William G. Fairbrother (ORCID: https://orcid.org/0000-0002-6312-5615)
- Alger M. Fredericks
- Sean F. Monaghan (ORCID: https://orcid.org/0000-0003-1490-3043)
- Emanuele Raggi
- Brandon E. Armstead (ORCID: https://orcid.org/0000-0002-8774-7304)
- Maya Cohen
- Gerard J. Nau
- Mitchell M. Levy
Institutions
- Brown University (US)
- Rhode Island Hospital (US)
Publication Details
- Journal
- Shock
- Published
- 2026-02-13
- DOI
- https://doi.org/10.1097/shk.0000000000002756
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00