Comprehensive evaluation of Chokyungjongok-tang, a traditional herbal prescription: HPLC-based quality assessment, genotoxicity, anti-inflammatory efficacy

These findings indicate that CKJOT showed no evidence of genotoxicity in OECD/MFDS guideline-compliant in vitro and in vivo assays under the tested conditions, and that it modulated selected inflammatory mediators in LPS-stimulated RAW264.7 macrophages in vitro.

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Publication Details

Journal
Journal of Ethnopharmacology
Published
2026-02-16
DOI
https://doi.org/10.1016/j.jep.2026.121391
Primary Topic
Ginseng Biological Effects and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Comprehensive evaluation of Chokyungjongok-tang, a traditional herbal prescription: HPLC-based quality assessment, genotoxicity, anti-inflammatory efficacy

Jihye Jang, Mee-Young Lee, Youn-Hwan Hwang, Hyeun-Kyoo Shin et al.
Journal of Ethnopharmacology
Ginseng Biological Effects and Applications
article

Comprehensive evaluation of Chokyungjongok-tang, a traditional herbal prescription: HPLC-based quality assessment, genotoxicity, anti-inflammatory efficacy

Jihye Jang, Mee-Young Lee, Youn-Hwan Hwang, Hyeun-Kyoo Shin, Sae-rom Yoo
article en

Abstract

These findings indicate that CKJOT showed no evidence of genotoxicity in OECD/MFDS guideline-compliant in vitro and in vivo assays under the tested conditions, and that it modulated selected inflammatory mediators in LPS-stimulated RAW264.7 macrophages in vitro.

Journal of EthnopharmacologyVol. 363
Korea Institute of Oriental Medicine (KR)
Openalex Percentile: Top 54%
Ginseng Biological Effects and Applications
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