Forest Bathing (Shinrin-yoku) and Preventive Medicine: Immune Modulation, Stress Regulation, Neurocognitive Resilience, and Neurological Health

<b>Background/Objectives:</b> Forest bathing (<i>Shinrin-yoku</i>) is a nature-based approach with potential preventive health relevance. This review summarizes evidence on its effects on immune function, stress physiology, and neuroprotective pathways. <b>Methods:</b> A narrative review of peer-reviewed studies was conducted using major scientific databases, including observational and interventional research assessing physiological or neurocognitive outcomes following forest exposure. <b>Results:</b> Forest bathing is associated with enhanced natural killer (NK) cell activity, modulation of inflammatory cytokine profiles, reductions in cortisol levels, and shifts toward parasympathetic autonomic dominance. Evidence also suggests a contributory role of tree-derived biogenic volatile organic compounds and phytoncides in immune and stress-regulatory effects. Emerging findings indicate potential benefits for cognitive restoration, emotional regulation, and neurotrophic signaling; however, substantial heterogeneity in study design, exposure characteristics, and outcome measures limits direct comparability and causal inference. <b>Conclusions:</b> Current evidence supports forest bathing as a promising, low-risk strategy for supporting immune resilience, stress regulation, and neurocognitive well-being within a preventive health framework. Preliminary findings also suggest potential benefits in chronic neurological conditions, supporting its neuroprotective role within multimodal neurorehabilitation strategies. Standardized intervention protocols, mechanistic biomarkers, and longitudinal studies are required to strengthen clinical relevance and guide evidence-based integration into public health and lifestyle medicine.

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Publication Details

Journal
Medical Sciences
Published
2026-02-15
DOI
https://doi.org/10.3390/medsci14010095
Primary Topic
Urban Green Space and Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Forest Bathing (Shinrin-yoku) and Preventive Medicine: Immune Modulation, Stress Regulation, Neurocognitive Resilience, and Neurological Health

Giovanni Nicola Roviello, Soumya Shah, Arnab Bandyopadhyay
Medical Sciences
Urban Green Space and Health
article

Forest Bathing (Shinrin-yoku) and Preventive Medicine: Immune Modulation, Stress Regulation, Neurocognitive Resilience, and Neurological Health

Giovanni Nicola Roviello, Soumya Shah, Arnab Bandyopadhyay
article en

Abstract

<b>Background/Objectives:</b> Forest bathing (<i>Shinrin-yoku</i>) is a nature-based approach with potential preventive health relevance. This review summarizes evidence on its effects on immune function, stress physiology, and neuroprotective pathways. <b>Methods:</b> A narrative review of peer-reviewed studies was conducted using major scientific databases, including observational and interventional research assessing physiological or neurocognitive outcomes following forest exposure. <b>Results:</b> Forest bathing is associated with enhanced natural killer (NK) cell activity, modulation of inflammatory cytokine profiles, reductions in cortisol levels, and shifts toward parasympathetic autonomic dominance. Evidence also suggests a contributory role of tree-derived biogenic volatile organic compounds and phytoncides in immune and stress-regulatory effects. Emerging findings indicate potential benefits for cognitive restoration, emotional regulation, and neurotrophic signaling; however, substantial heterogeneity in study design, exposure characteristics, and outcome measures limits direct comparability and causal inference. <b>Conclusions:</b> Current evidence supports forest bathing as a promising, low-risk strategy for supporting immune resilience, stress regulation, and neurocognitive well-being within a preventive health framework. Preliminary findings also suggest potential benefits in chronic neurological conditions, supporting its neuroprotective role within multimodal neurorehabilitation strategies. Standardized intervention protocols, mechanistic biomarkers, and longitudinal studies are required to strengthen clinical relevance and guide evidence-based integration into public health and lifestyle medicine.

Medical SciencesVol. 14(1)
Federico II University Hospital (IT), Institute of Biostructure and Bioimaging (IT), National Research Council (IT), University of Naples Federico II (IT)
Life in Land
Openalex Percentile: Top 56%
Urban Green Space and Health
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